The Complement System (another amazing thing our body is capable of doing) consists of proteins that combat infection through inflammation, phagocytosis and cytolysis. It is a defensive system that is made up of over 30 proteins produced by the LIVER and found circulating in blood plasma and within tissues throughout the body. These proteins kill microbes by phagocytosis, cytolysis, and inflammation.
The important proteins that lead the way are our C1- C9 complement proteins. They are all INACTIVE and only become ACTIVATED when split by ENZYMES into ACTIVE fragments. Our C3 protein is one that is split into ACTIVATED fragments that carry out the orders to destroy bad things joining the C1-C9 proteins.
C3 is activated in three different ways:
1) Classical Pathway
2) Alternative (go figure) Pathway
3) Lectin Pathway
Any pathway don't matter, activates C3 our goal... and once doing so C3 begins a sequence of reactions that consists of phagocytosis, cytolysis, and inflammation. The steps are:
1) Inactivated C3 splits into activated C3a and C3b. (2) C3b bind to the surface of a microbe (bad thing), then receptors on phagocytes attach to the C3b. C3b does a magic trick and enhances phagocytosis by coating the microbe with a process called opsonization which promotes attachment of a phagocyte to a microbe. (3) C3b then starts its own series of reactions that cause cytolysis. C3b splits C5 into activated C5a and C5b. C5b attaches to C6 and C7 which attach and attack the plasma membrane of an invading microbe. (4) C8 and several C9 molecules join the other complement proteins and together form a cylinder-shaped membrane attack complex (THE MAC ATTACK!!!) They literally puncture holes into the cell membrane of the bad cells and it results in cytolysis, the bursting of cells due to the extracellular fluid flowing in through the channels. (5) Wondering what happened to C3a and C5a? They bind to mast cells and they cause a release of histamine (UH OH!), which increases blood vessel permeability during inflammation. AND C5a... attracts phagocytes to the site of inflammation which ya know... takes care of microbial cells even more!!!
This along with the lymphatic system is so important just to know about. Its amazing how our body has like a back up plan if something doesn't catch the "bad" stuff. Its like Scottie Pippen to Michael Jordan or something... He couldn't do it all right?
high proteins!!
ReplyDeleteBetts here is a list of foods rich in proteins so you can gain some muscle.... lol
whey (supplement found in health food stores)
chicken breast
turkey breast
salmon
tuna
cottage cheese
swordfish
haddock
lean ground turkey
round steak
sirloin steak
lean ground beef
orange roughy
eggs
pork
crab
lobster
shrimp
buffalo
These are some but not all of the foods I recommend for a healthy body and mind. Eating healthy will help prevent the "bad Stuff" and help our body fight the inevitable that happens regardless of what we eat or do."These proteins kill microbes by phagocytosis, cytolysis, and inflammation."
good advice from Rob, however, if you want to gain muscle mass you also, in addition to eating the correct portion of protein as well as fruits and veggies, need to lift weights 3 x per week to develop your 6 pak. Living with a diabetic and taking nutritional classes, I learn too much protein daily, is not good as your body can excrete excess amount of ketones therefore putting your body into starvation mode called ketoacidosis. This is when your body will begin eating muscle and not fat. Don't forget your cardio the days you don't lift weights.
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