Proteins cause proteins already in the cell to activate or deactivate. If it is active it will deactivate, and vice versa.
A hormone attachs to a protein causing shape change which changes the G Protein attached on the interface of the cell membrane. G Protein consists of Alpha, beta, and ganna. The alpha is realeased after exchanging GDP for GTP and attaches to a different enzyme on the interface of the cell membrane. It then scoops up ATP and releases a phosphate and creates cAMP where the 2nd messenger system kicks in. cAMP released binds to PKA takes a scoop of ATP, rips another phosphate which = ADP, and phosphate attachs to another enzyme & so on & so on.
Sam, please tell me that you made that image because it is AWESOME.
ReplyDeleteI think that cAMP is the second messenger, not just where it kicks in. But your overall description of the pathway was helpful, thanks!
Dani
Sam,
ReplyDeleteI thought your image was great. Your description was very helpful. In parts it could have been a little more clear.
Jake